💡 What is Exemestane (Aromasin) 25 mg?

🛡️ Mechanism of Action

• • Aromatase Inhibitor: It blocks the aromatase enzyme, which converts androgen hormones into estrogen in the body. 

  • Irreversible Binding: It binds permanently (suicide inhibition) to the enzyme, effectively shutting down estrogen production. 

  • Halts Cancer Growth: By severely lowering estrogen levels, it starves the cancer cells that rely on this hormone to grow. 

📌 Main Uses

• • Sequential Therapy: Taken after 2–3 years of tamoxifen treatment to complete a total 5-year course of hormone therapy. 

  • Advanced Breast Cancer: Used when the cancer has progressed despite other treatments like tamoxifen. 

⚠️ Important Usage Details

• • Dosage: The standard dose is one 25 mg tablet taken once daily, preferably after a meal. 

  • Bone Health: Lowering estrogen can cause bone loss (osteoporosis), so regular bone density monitoring is usually recommended.